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Modafinil vs Vyvanse For Narcolepsy And ADHD

Modafinil vs Vyvanse For Narcolepsy and ADHD

People in the world deal with various psychological disorders for several reasons in their lives. Attention Deficit Hyperactivity Disorder and Narcolepsy which is a type of sleeping disorder are examples of mental disorders that people suffer from. Fortunately, there are medications available to treat these disorders namely Vyvanse and Modafinil. As both are used for different mental disorders so, there will be Modafinil vs Vyvanse differences.

Healthcare experts arrange to buy these medicines online for effective treatment of ADHD, narcolepsy, shift work disorder (SWD), or obstructive sleep apnea (OSA) in adults. ADHD is mainly found in childhood as well as adults. Children and adults who suffer from impulsivity, inattentiveness, and hyperactivity require these medicines to get relief from this disorder.

If anyone wants to know more details about the comparison between modafinil and Vyvanse, their similarities, and the management of their usage then stay tuned to this page till the last.

Comparison: Modafinil vs Vyvanse

What is Modafinil?

Modafinil drug is used to treat the problem of excessive sleepiness caused by various reasons, such as shift work disorder (SWD), sleep apnea, narcolepsy, fatigue, depression, and ADHD. This medication helps by promoting wakefulness and stopping patients from feeling sleepy.

It is the generic name and its brand name is Provigil. It is in a class of drugs called wakefulness-promoting agents, and this medication works by changing the amount of a few natural substances, present in the brain, that control sleep and wakefulness.

In the United States, this drug was approved by the Food and Drug Administration (FDA) for the treatment of narcolepsy, obstructive sleep apnea, and sleep work shift disorder in adults, but it is not approved for patients below the age of 17 years.

Modafinil medicine is a non-amphetamine central nervous system (CNS) stimulant with wakefulness properties. This drug is classified as a controlled substance class IV drug.

Modafinil is a first-line treatment for sleep work shift disorder and narcolepsy. This drug is purchasable only with your healthcare expert’s prescription.

What is Vyvanse?

Vyvanse is a prescription medication, used to treat attention deficit hyperactivity disorder (ADHD) and binge-eating disorder in adults. This medication is a central nervous system (CNS) stimulant that affects the chemicals in the brain and nerves that lead to hyperactivity and impulse control.

Lisdexamfetamine is the generic name and the brand name is Vyvanse. It helps to increase ability to stay focused, pay attention, and stop fidgeting. This is a CNS stimulant, and it is not used for the treatment of obesity and/or overweight.

Vyvanse was approved by the Food and Drug Administration (FDA) in the year 2007 for the treatment of ADHD in adults and in 2015, it was approved for the treatment of binge-eating disorder.

Uses: Modafinil vs Vyvanse Medications

Vyvanse uses:

  • This drug is used in the treatment of ADHD, in people who are older than 6 years.
  • This medication is used to treat moderate to severe binge-eating disorder (BED) in adults.

Modafinil Uses:

It is used to improve wakefulness in people who are suffering from:

  • Obstructive sleep apnea/ hypopnea syndrome (OSAHS)
  • Shift work sleep disorder (SWSD)
  • Narcolepsy

Dose & Dosages of Vyvanse and Modafinil Drugs

Vyvanse forms and strengths:

This drug comes in two forms:

  • Capsule
  • Tablet

The strengths of the tablet and capsule are as follows:

Tablets:- 10 mg, 20 mg, 30 mg, 40 mg, 50 mg and 60 mg strengths.

Capsules:- 10 mg, 20 mg, 30 mg, 40 mg, 50 mg, 60 mg and 70 mg strengths.

Modafinil forms & strengths:

It is available in the branded name Provigil in a single form

  • Tablet form

The strengths of modafinil(Provigil) tablets are mentioned below:

Dosages of Vyvanse medication:

  • The initial dose for patients suffering from (ADHD) and (BED) is 30 mg per day.
  • The dosage of the drug for adults and children is the same for the treatment of ADHD. However, it is not administered to children for the treatment of Binge Eating Disorder.
  • The highest dose of 70 mg per day, is recommended by your healthcare expert if necessary, for better treatment.

Dosages of Modafinil medication:

  • For Narcolepsy & Obstructive sleep apnea (OSA)
  • Patients can take a single dose of 200 mg once a day, but the maximum dose should not exceed 400 mg per day.
  • For Shift work disorder (SWD)
  • SWD patients can consume a dose of 200 mg once a day before starting their work shift or routine.

Side Effects: Modafinil vs Vyvanse

Each of the drugs has certain side effects which are mentioned below.

Common side effects of modafinil drug:

  • Headache
  • Feeling nervous or anxious
  • Back pain or joint pain
  • Upset stomach
  • Stuffy nose
  • Problem in sleeping
  • Mouth sores
  • Fever

Serious side effects of modafinil drug:

  • Dryness of skin
  • Muscles stiffness
  • Nervousness
  • Anxiety
  • Tiredness and weakness in the body
  • Rapidly changing mood
  • Depression
  • Increased blood pressure
  • Fast and pounding heartbeat
  • Excitement or agitation
  • Indigestion
  • Hallucinations

Common side effects of Vyvanse drug:

  • Nausea
  • Vomiting
  • Stomach pain
  • Diarrhea
  • Constipation.
  • Dry mouth
  • Loss of appetite
  • Weight loss
  • Sleep problems (insomnia)
  • Dizziness
  • Feeling anxious or irritable
  • Fast heart rate
  • Feeling jittery

Serious side effects of Vyvanse medicines:

  • Redness of the skin or skin allergy
  • Shivering
  • Sore throat
  • Over-reactive reflexes
  • Poor coordination
  • Puffiness or swelling of the eyelids or around the face, lips, eyes, tongue
  • Irritated eyes – become red
  • Breathing problems
  • Problem in swallowing

Precaution of Modafinil and Vyvanse:

  • Tell your healthcare expert about any allergies to any of these medications.
  • Both drugs are habit-forming, and you should never share these medications with another person, who has a history of drug abuse or addiction.
  • You should store your medications at room temperature away from heat, moisture, and light.
  • Individuals should avoid overdosing on these drugs because they can show serious symptoms and can be fatal.
  • Patients should be informed about their medical history before starting the treatment.
  • These medications can interact with other drugs, herbal or other vitamin supplements. Do not take any other medicines unless you have discussed with your doctor.
  • These medications are prescription-only drugs, so you should be prescribed by your doctor.


Concluding the blog Modafinil vs Vyvanse, we have understood that both medications differ from each other. Modafinil and Vyvanse have both advantages and disadvantages in treating these psychological disorders. This blog may not include all the information regarding these medications, So, it will be helpful for you to consult with a healthcare professional, if you have been dealing with these disorders for a long time. Hope, this blog will be helpful and informative for you!

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