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Nucynta vs Hydrocodone For Pain Relief

Nucynta vs Hydrocodone

Pain! This word might irritate many of us. Some pains are easily identifiable, while it might be difficult to detect the cause behind such pains. Fortunately, there are also medicines available to treat them including Nucynta and hydrocodone. This blog will provide a comparison on Nucynta vs hydrocodone.

Let’s see how both drugs are different from each other.

Comparison: Nucynta vs Hydrocodone

What is Nucynta?

The drug belongs to the drug class of opioids which is sometimes considered a narcotic. This is a branded drug and is prescribed to treat moderate to severe pain in individuals.

This is useful in treating pain, which cannot work effectively with other medications. This medicine does not require daily consumption, you cannot consume the medicine on the basis of the symptoms that you are experiencing currently.

What is Hydrocodone?

As mentioned in the overview, hydrocodone also belongs to the drug class of opioids and antitussives. This drug is a combination of hydrocodone and acetaminophen. The uses of this hydrocodone drug will be discussed below briefly.

Uses: Nucynta vs Hydrocodone:

Nucynta uses:

  1. Helpful in Treating Post Operative Pain
  2. Useful in Managing Chronic Pain
  3. Distressing Injury Pain
  4. Neuropathic Pain
  5. Relief from Cancer Pain

Uses of Hydrocodone:

  1. Sharp Pain Relief
  2. Beneficial in Managing Chronic Pain
  3. Reduces Cough in an Individual
  4. Manages Pain Associated with Cancer
  5. Presides over Post-Surgical Pain

Dosage and Strength of Nucynta and Hydrocodone

Nucynta Dosages-

  • Immediate Release Nucynta dosages for An Adult in Pain is as follows-
  • Initial Dosage: Consume 50 to 100 mg orally as needed when suffering from pain.
  • The patient can take the second dose for 1 hour after the consumption of the first dose if required.
  • People can take a maximum Dosage of 700mg on the first day and 600 mg subsequently on other days if required.

Dosage of Hydrocodone-

Usual Dose for an Adult

The initial dosage is 10mg orally in every 12 hours duration for not opioid-tolerant people. In every 24 hours duration, they can take the dose of 20 mg orally. The other available dosage strengths of hydrocodone are-

Side Effects of Nucynta vs Hydrocodone Drug:

Both Pain relief medicines have common and serious side effects. If you suffer any of them consultation with a doctor is very important.

Nucynta Side-effects-

  • Noise while Breathing
  • Feeling Very Warm
  • Extreme Drowsiness
  • Dizziness
  • Confusion
  • Multiple Episodes of Seizures
  • Serotonin Ailments: Anxiety, Hallucination and Fever, Stiffness in muscles, Low Levels of Coordination
  • Nausea
  • Vomiting
  • Decreased Appetite

Side effects of Hydrocodone-

  • Drowsiness
  • Light breathing
  • Dizziness
  • Vomiting
  • Nausea
  • Dry mouth
  • Lethargy
  • Weakened physical activity
  • Itching

Some severe side effects of Hydrocodone include:

  • Feeling of passing out
  • Seizures
  • Rapid heart rate leading to heart failure
  • Confusion
  • Painful urination
  • Stomach pain and constipation

The drugs that are advised to not take with Nucynta:

Some medications are as follows that are not prescribe to take with Nucynta:

  1. Diseases like allergies, asthma, agitated bladder, blood pressure medications, etc.
  2. Other opioid medications.
  3. Muscle relaxants, Medications used for treating sleeping disorders, and some other kinds of drugs that show drowsy effects on the body.
  4. Sedatives that are made of benzodiazepine, such as Klonopin, Valium and Xanax.
  5. Remedies that affect serotonin levels, such as antidepressants, migraine medicines, and stimulants.

The drugs that are advised to not be taken with Hydrocodone :

  1. Cold, allergy, COPD (Chronic Obstructive Pulmonary Disease) cured medication.
  2. Medicines that are helpful in treating irritable bowl.
  3. Other opioid medications.
  4. Avoid taking sedatives like Valium, Lorazepam, Xanax and Klonopin.
  5. Drugs that enhances your breathing and sleeping process.

Precautions for Both Drugs:

  • Don’t use these drugs without consulting a licensed healthcare professional about your health history.
  • Avoid these two drugs if you have asthma problems, or constipation problems.
  • It is advised not to take alcohol with these pain relief drugs. Because it may cause dizzy or drowsy.
  • Don’t misuse them otherwise, it can lead to addiction, overdose, and even death.


Concluding the blog, we have understood the Nucynta vs Hydrocodone comparison. Both are used to treat various pain in individuals. It is advised not to ignore if a patient sees little changes to their health after taking these drugs.

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