Opana ER is an analgesic or opioid analgesic drug, used for the management of moderate to severe pain conditions. Initially, Opana oral medication is available in two forms, immediate-release (IR) tablets, and extended-release (ER) tablets. Opana ER 5 mg is an extended-release formulation of Opana. It aims at the treatment of long-lasting pain such as that caused by several kinds of cancer, back pain, etc.
This medicine is applied specifically to those patients who need continuous or around-the-clock management of opioids for pain treatment in the long term. Its active component Oxymorphone belongs to a high abuse potential category of drugs.
Notably, Opana ER was withdrawn from the market due to major safety issues. It was responsible for several dangerous, life-threatening diseases, namely, HIV, hepatitis C virus, and thrombotic microangiopathy.
Mechanism of Opana ER 5 mg
Oxymorpholone, the medicinal component of Opana ER, is a synthetic opioid agonist. It mainly exhibits its analgesic abilities by connecting with mu-opioid receptors within the central nervous system (CNS). Through the activation of these receptors, Oxymorphone regulates pain response and perception, provoking a response that ends up relieving pain. In other words, it may transform the emotional reaction to pain and, consequently, the feeling of being painless remains.
Uses of Opana ER Tablet
Chronic Pain Management: Opana ER is normally prescribed first to people suffering from moderate to severe chronic pain that requires round-the-clock treatment with opioids. It is mostly used when other painkillers appear to be not suitable for a patient, either due to side effects or failure to provide adequate relief.
Cancer Pain: In the scenarios of cancer pain that is not completely controlled by the other opioids, then the Opana ER can be prescribed to alleviate the pain.
Neuropathic Pain: In special cases of neuropathic pain, where nerves are damaged or dysfunctional, Opana ER may be used in treating that particular condition to ease some of the symptoms experienced.
Postsurgical Pain: Opana ER can also be used for long-term pain management, especially after major surgery, when the patient is undergoing a long recovery process.
Dosage of Opana Pills
Opana drug is available in varying dosage strengths of immediate-release (IR) and extended-release (ER) tablets.
IR Tablets :
- Opana IR 5 mg
- Opana IR 10 mg
ER Tablets :
- Opana ER 5 mg
- Opana ER 7.5 mg
- Opana ER 10 mg
- Opana ER 40 mg etc.
Dose
Opana ER tablets should be swallowed whole at one time. An individual must follow it precisely as recommended by a healthcare expert. Nonetheless, a doctor may advise taking it without food, at least an hour before eating or 2 hours after that. In general, the dosing time intervals between two subsequent doses should not exceed 12 hours.
Side Effects of Opana ER 5 mg Medicine
- Night blindness
- Neonatal Opioid Withdrawal Syndrome
- Cough
- Fever
- Angioedema
- Twitching
- Shivering
- Anaphylaxis
- Nausea
- Mental depression
- Agitation
- Gastrointestinal Adverse Reactions
- Restlessness
- Abdominal pain
- Pain while urinating
- Constipation
- Pruritus
- Somnolence
- Confusion
Precautions
- Taking Opana ER along with alcohol can lead to serious health issues, including death.
- Opana is not intended for use in pediatric patients.
- Avoid any kind of breaking, chewing, or crushing of the tablet to reduce unwanted effects because an overdose in the patients is a possible reaction. Opana ER formulation is so designed that its active ingredients are released gradually.
- This drug is normally given by a doctor after diagnosing the problem. The dosage should be administered by a healthcare specialist only.
- This drug may cause severe tiredness or fainting. One must not be assigned to heavy duties, which include operating automobiles and other machinery.
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