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Flmodafinil vs Modafinil: What is the Difference between Them?

Flmodafinil vs Modafinil What is the Difference between Them

Sleep is one of the most important requirements of people, and is very critical to both mental and physical health. If you are not getting enough sleep of proper quality, it can affect your health in many different ways. The risk of many diseases and disorders may rise such as sleep disorders, hypersomnia, sleep apnea, insomnia, narcolepsy, etc. Flmodafinil vs Modafinil, as both are used to treat these disorders, may have some differences in some cases.

Most of the people in the United States of America are suffering from various sleep disorders because of an inactive lifestyle. The main reasons for sleep disorders are physical, mental, and emotional problems of day-to-day life. Sleeping problems can affect the mental and physical health of an individual.

Excess sleep and lack of sleep, both, are associated with many chronic diseases such as diabetes and heart disease.

In this blog, we are going to learn about the two drugs Flmodafinil and modafinil which are used to treat the problem of sleep disorders. And also about their uses, dosages, side effects, and precautions.

Introduction of Both Medications: Flmodafinil vs Modafinil

What is Flmodafinil?

Flmodafinil is commonly known as CRL-40, 940, Lauflumide, and Bisfluoromodafinil. This medication is a nootropic or a smart drug or cognitive function booster that is used to treat problems such as narcolepsy, shift work disorder (SWD), and sleep apnea.

Flmodafinil is not an FDA-approved drug, and it is not a prescription medication, but it is used for treating sleep disorders and narcolepsy. The effects of this medicine last longer than modafinil.

This medication is an effective and safe smart drug, and it helps in boosting mood, concentration and cognitive abilities.

What is Modafinil?

Modafinil is the generic name, whereas Provigil is a brand name of this drug. It is in a class of drugs called wakefulness-promoting agents, and this drug works by changing a few amounts of natural substances, which are present in the brain, that control sleep and wakefulness in the person

This drug is a first-line treatment and is used to treat the problem of excessive sleepiness caused by various reasons, such as narcolepsy, shift work disorder (SWD), sleep apnea, and ADHD. This medication helps by promoting wakefulness and stopping patients from feeling sleepy.

In the United States, the Food and Drug Administration (FDA) approved this drug for the treatment of obstructive sleep apnea, shift work disorder, and narcolepsy. Modafinil is not approved for patients who are less than the age of 17 years by the FDA.

It is a non-amphetamine central nervous system (CNS) stimulant with wakefulness properties. This drug belongs to a class of medications called stimulants and is classified as a Schedule IV prescription drug.

Dose & Dosage:

Both medicines have various forms and strengths as mentioned below-

Flmodafinil forms & strengths

This drug is available in different forms-

  • Liquid form
  • Tablet form
  • Powder form

There are flmodafinil dosage available in various strengths such as-

  • Initial Doses of Flmodafinil are 12.5 mg – 25 mg:- Patients who are sensitive to any other medication can start their dosage of 12.5 mg per day and those who have experienced drugs like modafinil or a similar compound can take the dosage of 25 mg every day.
  • Flmodafinil Maximum Dosage 50 mg -100 mg:- Split the dose into 25 mg – 50 mg and take one half of the medicine, early in the morning when you wake up, and the remaining half dose at lunchtime every day.
  • Flmodafinil Maximal 150 mg or more:- 150 mg of Flmodafinil drug is not administered.

Modafinil forms & strengths

The drug is available in a single form-

  • Tablet form

Strengths of Modafinil tablet:

The Modafinil is avail in the the brand name Provigil and available in the dosage strengths as follows-

Dosages of Modafinil medication

  • Narcolepsy & Obstructive sleep apnea (OSA):- Individuals can take a single dose of 200 mg once in a day, but the maximal dose should not exceed 400 mg per day.
  • Shift work disorder (SWD):- Patients can take a dose of 200 mg once a day before starting their work shift or routine.

Uses: Flmodafinil vs Modafinil

Uses of Flmodafinil

This drug is used to increase attention span, memory power, and energy level, elevate mood, and help treat various problems of sleep disorders such as shift work disorder, narcolepsy, and sleep apnea.

Uses of Modafinil

Modafinil is used for the treatment of obstructive sleep apnea/hypopnea syndrome (OSAHS), shift work sleep disorder (SWSD), narcolepsy, attention-deficit/hyperactivity disorder (ADHD), anxiety and depression.

What are the Benefits of Flmodafinil and Modafinil?

Flmodafinil benefits in different ways, they are:

  • It helps to improve recall and retention.
  • Calming effect on the mind and helps to reduce aggressiveness.
  • It enhances the learning power of an individual.

Modafinil benefits are listed below:

  • Concentration power and focus are increased
  • Boosts mental health and physical energy
  • Reduces fatigue

Side Effects of Flmodafinil & Modafinil Medications:

Flmodafinil vs Modafinil, both have different side effects as follows-

Flmodafinil drug’s side effects :

  • Nausea
  • Headache
  • Insomnia
  • Loss of appetite
  • Diarrhea
  • Restlessness

Modafinil medication’s side effects :

  • Dry mouth
  • Back pain
  • Nervousness
  • Anxiety
  • Difficulty in sleeping
  • Dizziness
  • Runny nose
  • Indigestion
  • Diarrhea
  • Chest pain
  • Loss of appetite
  • Nausea
  • Headache

Modafinil Serious side effects:

  • Vertigo
  • Fast heartbeat
  • Confusion
  • Constipation
  • Depression
  • Tremor


  • Individuals should inform the doctor about their medical history before starting a treatment course that involves these drugs.
  • Tell your healthcare expert about any allergy from any of these medications.
  • Keep the medicines out of children’s reach.
  • Always drink an adequate amount of water so that you feel hydrated.
  • Alcohol should be avoided while taking these medications.


In conclusion, Flmodafinil vs Modafinil, both differ from each other in some cases as mentioned in the blog. Although they treat sleeping disorders, both have advantages and disadvantages. So, it is important to consult with a health specialist before or after taking them. Hope, this blog will be helpful to you!

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