Medical Advice

Lortab vs Vicodin For Pain: Understanding the Similarities and Differences

Lortab vs Vicodin

Nowadays, pain is one of the most common medical issues. Many people are suffering from several pain-related conditions. Lortab and Vicodin are the most common drugs that can be used to treat individuals with acute to chronic pains. In this blog, we are going to discuss both medications and analyze Lortab Vs Vicodin comparison.

Both of these drugs are known as pain-relieving medicines and belong to the opioid analgesics drug class. These opioid medicines are used to treat moderate to severe pain that is caused by different types of injuries and several other health-related complications.

Also sometimes pain occurs in patients due to various conditions, including back pain, swelling, and physical pain. There are other drugs that can treat All of these pains including Paracetamol, Aspirin, Oxycontin, Oxycodone, etc., including Lortab medicine.

Comparison: Lortab vs Vicodin Drugs

What is Lortab Medicine?

Lortab drug is a prescription-only medicine. It is used to treat mild to severe pain that is caused by various injuries, accidents, and various other complications. This drug has the potential to reduce swelling and can also restrict the formation of mucus.

Lortab is a branded medicine that contains hydrocodone and acetaminophen. Hydrocodone is a narcotic painkiller that helps to prevent certain pain signals by binding to opioid receptors in the brain and spine. Opioid medications can trigger sleepiness in certain cases.

What is Vicodin Medicine?

Vicodin is an opioid painkiller that is used to relieve the severity of pain that is caused by accidents, injuries, etc. This medicine is also helpful for relieving severe back pain. The main components used in manufacturing this branded drug are Acetaminophen and Hydrocodone which are also generic drugs for Vicodin medicine. It is a prescription-only drug.

Vicodin drug is commonly prescribed by healthcare experts or physicians when a different type of treatment is required and it is known as a short-term pain relieving medication. This drug functions on the Central Nervous System (CNS) in the brain to stimulate the brain chemicals that are responsible for different kinds of pain whether it is acute, moderate, or chronic.


Lortab is a combination substance of hydrocodone and acetaminophen whereas Vicodin has the same composition that is similar to the drug Lortab.

The Function of Lortab And Vicodin Drugs

Lortab medicines act in the central nervous system (CNS) brain to change feelings and respond to the pain in the patient’s body. It starts working 1 hour after consumption and stays active in the body for up to 4 hours to provide relaxation to mild to severe pain.

Vicodin contains hydrocodone and acetaminophen in the form of active ingredients. Hydrocodone composition acts in the brain by changing the way of feeling and response to the pain in the individual’s body, while acetaminophen has low potential in pain relieving, and it is a more effective medicine for reducing fever than for relieving pain.

Uses of Both Drugs

Vicodin and Lortab are used to treat physical pain in the patient’s body during operation and pain after surgery, etc. But, both medications are also used for several off-label purposes which can be treated with these medicines, including neuropathic pain, tissue damage pain, and many more.

Dosage Information: Lortab vs Vicodin

A Doctor can suggest what foods to eat and avoid when prescribing Lortab and Vicodin drugs. These medicines help to prevent various medical problems that can harm the patient.

A physician may change the doses of both of these medications after diagnosing the patients. A list of some dosage strengths and forms of Lortab and Vicodin drugs, including:

1) Lortab

The dosage strength along with the form of Lortab medication are mentioned below:

Form of Oral Tablet

2) Vicodin

There are varied dosage forms and strengths of the Vicodin drug. The most common vicodin dosage strengths are –

Form of Oral tablet:

Form of Oral solution:

  • (7.5 mg / 325 mg)/15 ml
  • (10 mg / 300 mg) /15 ml
  • (10 mg / 325 mg) / 15 ml

Half-Life: Lortab vs Vicodin

Lortab starts to work in 1 hour after consuming and its effect can last up to 4 hours long in the patient’s body for providing relaxation to mild to severe pain.

Vicodin starts working in 1 hour after taking and its effect can last up to 4 hours.

Side Effects of Lortab and Vicodin Medications

While using these two drugs, both medications may cause some mild to severe side effects as follows.

  • Anxiety
  • Drowsiness
  • Dizziness
  • Stomach pain
  • Agitation
  • Fever
  • Vomiting or nausea
  • Drowsiness
  • Constipation
  • Blurred vision
  • Mood swings
  • Difficulty when urinating
  • Dry mouth
  • Hallucinations
  • Ringing ears
  • Fast heartbeat
  • Jaundice
  • Nervousness
  • Noisy breathing,
  • Trouble breathing
  • Feeling light-headed
  • Confusion
  • Unusual thoughts
  • Convulsions
  • Missed menstrual periods
  • Loss of interest in sex

Precautions for Lortab and Vicodin Drug:

  • Do not drive after consuming Lortab and Vicodin medication.
  • Before one starts using both two medicines, tell a doctor if they have any other drug allergies.
  • It is important to keep drugs away from children and pets.
  • If a patient takes other medication they are advised not to take these tablets without doctor’s recommendations.
  • Do not consume alcohol as it can interact with Lortab and Vicodin drugs, and may result in death.
  • All of these medicines should make feel dizzy and drowsy.
  • Pregnant women or breastfeeding women are not allowed to take these pills.
  • Do not share the dose of both of these drugs with other individuals who suffer from pain conditions.


So, we have seen that both Lortab and Vicodin are used in the management of pain in individuals. The combination of both drugs same i.e. both present the same substance namely hydrocodone and acetaminophen. Individuals are advised to take safety measures while taking the drugs. We have tried to explain all the information regarding these drugs in this blog. Hope this blog will be a helping hand in choosing the best medicine to manage pain.

Related Posts

Leave a Reply

Your email address will not be published. Required fields are marked *