Showing all 4 resultsSorted by popularity

Generic Soma 350 mg

In stock

Price range: $399.00 through $649.00
Buy Now This product has multiple variants. The options may be chosen on the product page

Generic Carisoprodol 350 mg

In stock

Price range: $399.00 through $649.00
Buy Now This product has multiple variants. The options may be chosen on the product page

Generic Soma 250 mg

In stock

Price range: $399.00 through $569.00
Buy Now This product has multiple variants. The options may be chosen on the product page

Generic Carisoprodol 250 mg

In stock

Price range: $399.00 through $569.00
Buy Now This product has multiple variants. The options may be chosen on the product page

Overview

Carisoprodol is a prescription-only generic medicine, which is used to treat muscle pain or pain from injury in people. Muscle pain can occur due to Lyme disease, fibromyalgia, polymyalgia rheumatica, and other diseases. Buy Carisoprodol Online or at any hospital pharmacy or at any nearby pharmacy with a prescription to cure pain.

The commonly used brand names of Carisoprodol generic variant medicine are Soma and Vanadom. It is the most common prescription medicine and is approved by the US FDA. The half-life of Carisoprodol medicine is 2.5 hours when taken orally for treating pain.

What carisoprodol is approved for

The FDA label covers “relief of discomfort associated with acute, painful musculoskeletal conditions.” In practice that means a pulled back muscle, a neck strain, a sprain, or muscle spasm after an injury. It’s meant to be used with rest, physical therapy and other measures, not instead of them.

It’s not approved for long-term conditions such as fibromyalgia, arthritis, chronic back pain, or nerve pain (for nerve pain, see Gabapentin). It also isn’t the answer for ordinary muscle cramps, which usually respond to hydration, stretching and electrolytes. See What Causes Muscle Cramps? and Best Drinks to Prevent Muscle Cramps.

How it works, and the meprobamate connection

Carisoprodol acts in the brain and spinal cord, not in the muscles. Its exact mechanism isn’t well understood. It appears to dampen nerve signaling and cause sedation, which reduces the perception of pain and spasm.

The liver converts carisoprodol into meprobamate, which was sold as the tranquilizer Miltown in the 1950s and is itself a Schedule IV drug. Meprobamate:

  • lasts much longer than carisoprodol (half-life ~10 hours vs. ~2)
  • acts on the same GABA-A receptors as benzodiazepines and barbiturates
  • explains much of carisoprodol’s sedation, its dependence potential, and the withdrawal symptoms after heavy use

That’s why carisoprodol can feel more like a sedative than a targeted muscle medicine, and why it combines so dangerously with other sedatives.

Your genes and carisoprodol

Short answer: a common genetic variation can leave some people with about four times as much carisoprodol in their blood.

Carisoprodol is broken down mainly by the liver enzyme CYP2C19. People who inherit low-activity versions of this enzyme (“poor metabolizers”) clear it much more slowly.

Group How common Effect
Normal metabolizers Most people Standard exposure
Poor metabolizers ~3–5% of people of European or African ancestry; ~15–20% of people of Asian ancestry About 4× higher carisoprodol exposure, lower meprobamate. More drowsiness.

Dosages:

The drug comes in different dosages and is available in the form of an oral tablet only. The dosage strengths of the Carisoprodol oral tablet are 250mg and 350mg. People can take this medicinal drug thrice a day for 2 to 3 weeks.

The brand Soma is also available in the form of oral tablets with strengths of Soma 250mg and Soma 350 mg.

Doctors recommend this medicine to young adults only and do not recommend children and adults above 65 years of age.

Dosing and the 2–3 week limit

Short answer: 250–350 mg up to four times a day, for no more than 2–3 weeks.

  • Dose: 250 mg or 350 mg three times a day and at bedtime.
  • 250 vs. 350 mg: in the trials behind the 250 mg approval, 250 mg relieved pain about as well as 350 mg, with less drowsiness. Many prescribers start there.
  • Why the time limit? Acute muscle injuries usually improve within 2–3 weeks, and there’s no good evidence for longer use. Longer courses raise the risk of dependence.
  • Kidney or liver disease: use with caution; the label has no specific dose adjustments.
  • Under 16 or over 65: safety and effectiveness haven’t been established. Muscle relaxants are on the Beers list of drugs to avoid in older adults because of sedation and falls.

Muscle relaxant matchup

Short answer: carisoprodol is the only common muscle relaxant that’s a controlled substance, and it’s rarely the first choice.

Carisoprodol Cyclobenzaprine (Flexeril) Methocarbamol (Robaxin) Tizanidine (Zanaflex)
Controlled? Schedule IV No No No
Approved for Acute musculoskeletal pain Acute muscle spasm Acute musculoskeletal pain Spasticity (MS, spinal cord injury)
Sedation High High Moderate High
Misuse potential Highest Low Low Low–moderate
Special cautions Meprobamate; withdrawal Anticholinergic effects; tricyclic-like Brown/green urine (harmless) Low blood pressure; liver tests; CYP1A2 interactions
Often chosen when… Others haven’t worked First-line for spasm Sedation must be minimized Spasticity, or at night
Compare n/a Soma vs. Flexeril Carisoprodol vs. Methocarbamol Tizanidine vs. Soma

Comparing with a pain reliever rather than another relaxant? See Carisoprodol vs. Tramadol and Tramadol vs. Flexeril.

Uses:

The work of Carisoprodol medicine is to control the brain and spinal cord in the nervous system. This helps to relax muscle stiffness in individuals.

Carisoprodol medicine is generally used along with physical therapy in the treatment of sprains, strains, and other muscle problems. People can take this medicine with or without food 3 times a day. Carisoprodol medicine is suggested to be taken for not more than two or three weeks. It is not used for long-term treatment of muscle pain in people.

This medicine has a higher chances of interacting with various other medicinal drugs. Some of these include Carbamazepine, Magnesium Oxybate, Oxymorphone, Zuranolone, Tramadol, Tapentadol, Sodium Oxybate, Codeine, Amoxapine, Calcium Oxybate etc.

Side Effects:

There are several side effects of this pain relief medicine. These are as follows:

  • Blurred vision
  • Headache
  • Hallucinations
  • Stomach pain
  • Nausea and vomiting
  • Sleeping problem (insomnia)
  • Dryness in mouth
  • Anxiety
  • Drowsiness
  • Dizziness or light-headedness
  • Diarrhea
  • Breathing, swallowing, and speaking problems
  • Chest pain
  • Pain or swelling in the eyes, arms and legs
  • Heartburn

Precautions:

  • People must consult with a doctor before taking Carisoprodol medicine.
  • Avoid consuming alcohol after taking Carisoprodol medicine.
  • It is advised to not drive a car or other vehicles after taking Carisoprodol medicine, since it can cause drowsiness in individuals.
  • Do not take this medicine when suffering from Porphyria condition that affects the skin and nerves in the person’s body.
  • Avoid taking other medicines without consulting with relevant doctors.
  • Women should not take this medicine during pregnancy and breastfeeding as it leads to harmful effects during their child’s birth.
  • Swallow it with a glass of water to avoid the bitter taste, of chewing, crushing, or breaking the tablet.

Why carisoprodol became a controlled substance

Carisoprodol was approved in 1959 and sold without federal controls for over 50 years. By the 2000s, emergency visits linked to it had risen sharply, often involving a combination of an opioid, a benzodiazepine and carisoprodol, a pattern known on the street as the “holy trinity.” That combination stacks three sedatives and is linked to fatal overdoses. The DEA placed carisoprodol in Schedule IV effective January 11, 2012. Several EU countries withdrew it entirely around 2008.

Drug interactions (reorganized)

The dangerous group: other sedatives. Any of these added to carisoprodol increases the risk of extreme sleepiness, slowed breathing, overdose and death:

  • Opioids: hydrocodone, oxycodone, codeine, tramadol
  • Benzodiazepines: Xanax, Valium, lorazepam, clonazepam
  • Sleep medicines, gabapentinoids, sedating antihistamines, alcohol

The enzyme group (CYP2C19):

  • Raise carisoprodol: omeprazole, esomeprazole, fluvoxamine
  • Lower carisoprodol, raise meprobamate: rifampin, St. John’s wort

Will it show up on a drug test?

Short answer: not on a standard 5-panel test, but on expanded panels, yes.

Carisoprodol and meprobamate aren’t included in basic workplace drug panels. Many expanded panels, pain-management screens and forensic tests do check for them. Meprobamate’s longer half-life extends the detection window.

For detection times, see How Long Does Carisoprodol Stay in Your System? and How Long Does Carisoprodol Stay in Your Urine?.

FAQ

Is carisoprodol the same as Soma?

Yes. Soma is the brand name; carisoprodol is the generic. They contain the same active ingredient. See Soma.

Is carisoprodol a narcotic or an opioid?

Neither. It’s a muscle relaxant. But it’s a Schedule IV controlled substance because its metabolite, meprobamate, causes sedation and dependence.

Can I stop taking carisoprodol suddenly?

After a short course at normal doses, usually yes. After longer or high-dose use, stopping abruptly can cause withdrawal: anxiety, insomnia, tremor, vomiting, and occasionally hallucinations or seizures. Ask your prescriber about tapering.

Can I drink alcohol while taking carisoprodol?

No. Alcohol adds to the sedation and raises overdose risk.

Why does carisoprodol make me so sleepy?

Sedation is its most common side effect, partly from meprobamate. If you’re a CYP2C19 poor metabolizer, levels run higher. Ask whether the 250 mg dose would work for you.

Can I take carisoprodol with tramadol?

Only if your prescriber specifically approves it. Both cause sedation, and tramadol adds seizure risk. See Carisoprodol vs. Tramadol.

Can I buy carisoprodol online without a prescription?

No. It’s a Schedule IV controlled substance in the US and requires a valid prescription. Legitimate pharmacies will always ask for one. The FDA’s BeSafeRx explains how to check.

Related