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Rozerem 16 mg

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Rozerem 8 mg

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Overview of Rozerem  Drug

Sleep disorder makes a person stay awake or have difficulty falling asleep, which is also known as Insomnia. The main reasons for this are due to physical inactivity, stress, depression, and bad sleeping habits. To treat this disorder you can buy Rozerem online or at any nearby pharmacy with a prescription.

The generic form as well as an active ingredient in this branded medication is Ramelteon. This drug belongs to the sedative and hypnotic class, this helps to maintain the sleep cycle in an individual. It helps to get asleep more quickly.

Rozerem has been approved by The U.S. FDA to treat insomnia in adults only. It is not recommended to treat children. It is not considered a controlled substance because it is unlikely used for misuse or abuse. Takeda Pharmaceuticals North America, Inc., is the manufacturer of this medicine.

Mechanism of Action of Rozerem Medication:

Rozerem consists of Ramelteon which is referred to as a melatonin receptor agonist. It has no affinity for the GABA receptor complex or receptors that binds with serotonin, noradrenaline, dopamine, cytokines etc. Melatonin is produced by the pineal gland, which maintains the circadian rhythms of sleep.

G protein-coupled receptors (Melatonin receptors) adhere to melatonin that is produced inside the body (endogenous). This drug has a stronger affinity to bind with MT1 and MT2 melatonin receptors than the MT3 receptor in the suprachiasmatic nucleus (SCN).

These two receptors have sleep-enhancing properties. This may increase sleep by maintaining the sleep-wake cycle (circadian rhythm). It speeds up the time that is required to fall asleep after turning off the lights (sleep onset). This is how Rozerem helps to treat insomnia.

Dose & Strength of Dose of Rozerem Medicine:

Rozerem drug is available in the form of an oral tablet with a dosage strength of 8 mg. It is pale orange-yellow colored, round shaped, and imprinted with TAK and RAM-8 on one side of the tablet. The administration of drugs is guided by a healthcare provider. This depends on the medical condition of a person.

The dose and its strength are administered by a doctor by examining the patient’s condition. The administration of dosages strength are as follows:-

In Adults

The 8 mg is an advised dose, which should be taken half an hour before getting into bed. One should not consume drugs instantly with or after having food that contains high calories. The maximum dose is 8 mg, and not beyond that dosage.

In Patients with liver failure (hepatic impairment)

Individuals who have problems related to their hepatic system, such as liver failure. Then, this medicine is not advised to be taken for adverse hepatic impairment. If there is mild liver failure then it may be consumed under the supervision of a doctor.

Uses of Rozerem Drug:

Rozerem medicine has many uses, these are as follows:-

1) Insomnia:-

Rozerem (Ramelteon) helps to decrease sleep latency. It is a time which is required to stay asleep. In general, it takes 10 to 20 minutes to fall asleep, however, this medication does in around 13 minutes. This sleeping pill enhances the sleep time of a person.

2) Sleep-wake Cycle Disorders:-

This drug is widely used to treat insomnia, however, it also helps to maintain sleep-wake cycle disorder. There is a biological clock inside an individual body that helps to wake up or sleep. This is synchronized with the environment. When this sync gets disrupted, the rhythm of sleep-wake gets affected and this is called Circadian rhythm sleep disorders.

Side Effects of Rozerem Medication:

Common Side Effects

  • Vertigo (dizziness)
  • Exhaustion (Fatigue)
  • Nausea
  • Extreme desire for sleep (somnolence)

Serious Side Effects

  • Ruminate about committing suicide
  • Hallucination
  • Discharge from nipples
  • Decrement in male hormone (Testosterone)
  • Loss of interest in sex
  • Fatal allergic reaction
  • Thought disorder (TH – which impacts thinking process and linguistic communication)
  • Raise Prolactin hormone level (females)

Safety Measures:

  • Alcohol should not be consumed while taking Rozerem drug.
  • One should inform a doctor about their medical history.
  • Due to drug interaction, it is suggested not to be taken with fluvoxamine.
  • It is not advised for children.
  • Patients who are having liver and kidney failure problems. They may consume this drug under the supervision of a healthcare professional, with caution.
  • The medicine should not be taken with or after eating a high-fat meal.